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Endogenously-expressed NH(2)-terminus of circumsporozoite protein interferes with sporozoite invasion of mosquito salivary glands
BACKGROUND: The circumsporozoite protein is the most abundant polypeptide expressed by sporozoites, the malaria parasite stage capable of infecting humans. Sporozoite invasion of mosquito salivary glands prior to transmission is likely mediated by a receptor/ligand-like interaction of the parasites...
Autores principales: | Kojin, Bianca B., Costa-da-Silva, André Luis, Maciel, Ceres, Henriques, Dayane Alves, Carvalho, Danilo O., Martin, Kelcie, Marinotti, Osvaldo, James, Anthony A., Bonaldo, Myrna C., Capurro, Margareth Lara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4785649/ https://www.ncbi.nlm.nih.gov/pubmed/26964736 http://dx.doi.org/10.1186/s12936-016-1207-8 |
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