Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics

Amsacrine analog is a novel chemotherapeutic agent that provides potentially broad antitumor activity when compared to traditional amsacrine. However, the major limitation of amsacrine analog is that it is highly lipophilic, making it nonconductive to intravenous administration. The aim of this stud...

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Detalles Bibliográficos
Autores principales: Fang, Yi-Ping, Chuang, Chih-Hung, Wu, Pao-Chu, Huang, Yaw-Bin, Tzeng, Cherng-Chyi, Chen, Yeh-Long, Liu, Ya-Ting, Tsai, Yi-Hung, Tsai, Ming-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786061/
https://www.ncbi.nlm.nih.gov/pubmed/27019595
http://dx.doi.org/10.2147/DDDT.S97161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786061/
https://www.ncbi.nlm.nih.gov/pubmed/27019595
http://dx.doi.org/10.2147/DDDT.S97161

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