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Animal models of myasthenia gravis: utility and limitations

Myasthenia gravis (MG) is a chronic autoimmune disease caused by the immune attack of the neuromuscular junction. Antibodies directed against the acetylcholine receptor (AChR) induce receptor degradation, complement cascade activation, and postsynaptic membrane destruction, resulting in functional r...

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Detalles Bibliográficos
Autores principales: Mantegazza, Renato, Cordiglieri, Chiara, Consonni, Alessandra, Baggi, Fulvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786081/
https://www.ncbi.nlm.nih.gov/pubmed/27019601
http://dx.doi.org/10.2147/IJGM.S88552