Role of Biomarkers in the Development of PARP Inhibitors

Defects in DNA repair lead to genomic instability and play a critical role in cancer development. Understanding the process by which DNA damage repair is altered or bypassed in cancer may identify novel therapeutic targets and lead to improved patient outcomes. Poly(adenosine diphosphate-ribose) pol...

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Detalles Bibliográficos
Autores principales: Ganguly, Bratati, Dolfi, Sonia C., Rodriguez-Rodriguez, Lorna, Ganesan, Shridar, Hirshfield, Kim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786099/
https://www.ncbi.nlm.nih.gov/pubmed/26997874
http://dx.doi.org/10.4137/BIC.S36679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786099/
https://www.ncbi.nlm.nih.gov/pubmed/26997874
http://dx.doi.org/10.4137/BIC.S36679

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