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Pediatric Primitive Neuroectodermal Tumors of the Central Nervous System Differentially Express Granzyme Inhibitors

BACKGROUND: Central nervous system (CNS) primitive neuroectodermal tumors (PNETs) are malignant primary brain tumors that occur in young infants. Using current standard therapy, up to 80% of the children still dies from recurrent disease. Cellular immunotherapy might be key to improve overall surviv...

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Detalles Bibliográficos
Autores principales: Vermeulen, Jeroen F., van Hecke, Wim, Spliet, Wim G. M., Villacorta Hidalgo, José, Fisch, Paul, Broekhuizen, Roel, Bovenschen, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786147/
https://www.ncbi.nlm.nih.gov/pubmed/26963506
http://dx.doi.org/10.1371/journal.pone.0151465