Metformin Induces Cell Cycle Arrest, Reduced Proliferation, Wound Healing Impairment In Vivo and Is Associated to Clinical Outcomes in Diabetic Foot Ulcer Patients

BACKGROUND: Several epidemiological studies in diabetic patients have demonstrated a protective effect of metformin to the development of several types of cancer. The underlying mechanisms of such phenomenon is related to the effect of metformin on cell proliferation among which, mTOR, AMPK and othe...

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Detalles Bibliográficos
Autores principales: Ochoa-Gonzalez, Fatima, Cervantes-Villagrana, Alberto R., Fernandez-Ruiz, Julio C., Nava-Ramirez, Hilda S., Hernandez-Correa, Adriana C., Enciso-Moreno, Jose A., Castañeda-Delgado, Julio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786193/
https://www.ncbi.nlm.nih.gov/pubmed/26963096
http://dx.doi.org/10.1371/journal.pone.0150900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786193/
https://www.ncbi.nlm.nih.gov/pubmed/26963096
http://dx.doi.org/10.1371/journal.pone.0150900

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