The Role of Epithelial Sodium Channel ENaC and the Apical Cl(-)/HCO(3)(-) Exchanger Pendrin in Compensatory Salt Reabsorption in the Setting of Na-Cl Cotransporter (NCC) Inactivation

BACKGROUND: The absence of NCC does not cause significant salt wasting in NCC deficient mice under basal conditions. We hypothesized that ENaC and pendrin play important roles in compensatory salt absorption in the setting of NCC inactivation, and their inhibition and/or downregulation can cause sig...

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Detalles Bibliográficos
Autores principales: Patel-Chamberlin, Mina, Varasteh Kia, Mujan, Xu, Jie, Barone, Sharon, Zahedi, Kamyar, Soleimani, Manoocher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786216/
https://www.ncbi.nlm.nih.gov/pubmed/26963391
http://dx.doi.org/10.1371/journal.pone.0150918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786216/
https://www.ncbi.nlm.nih.gov/pubmed/26963391
http://dx.doi.org/10.1371/journal.pone.0150918

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