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Stability of Ensemble Models Predicts Productivity of Enzymatic Systems
Stability in a metabolic system may not be obtained if incorrect amounts of enzymes are used. Without stability, some metabolites may accumulate or deplete leading to the irreversible loss of the desired operating point. Even if initial enzyme amounts achieve a stable steady state, changes in enzyme...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786283/ https://www.ncbi.nlm.nih.gov/pubmed/26963521 http://dx.doi.org/10.1371/journal.pcbi.1004800 |