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Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression

The nuclear receptors REV-ERBα and REV-ERBβ are transcription factors that play pivotal roles in the regulation of the circadian rhythm and various metabolic processes. The circadian rhythm is an endogenous mechanism, which generates entrainable biological changes that follow a 24-hour period. It re...

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Detalles Bibliográficos
Autores principales: Amador, Ariadna, Wang, Yongjun, Banerjee, Subhashis, Kameneka, Theodore M., Solt, Laura A., Burris, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786293/
https://www.ncbi.nlm.nih.gov/pubmed/26963516
http://dx.doi.org/10.1371/journal.pone.0151014