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Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression
The nuclear receptors REV-ERBα and REV-ERBβ are transcription factors that play pivotal roles in the regulation of the circadian rhythm and various metabolic processes. The circadian rhythm is an endogenous mechanism, which generates entrainable biological changes that follow a 24-hour period. It re...
Autores principales: | Amador, Ariadna, Wang, Yongjun, Banerjee, Subhashis, Kameneka, Theodore M., Solt, Laura A., Burris, Thomas P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786293/ https://www.ncbi.nlm.nih.gov/pubmed/26963516 http://dx.doi.org/10.1371/journal.pone.0151014 |
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