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Loss of ATP-Sensitive Potassium Channel Surface Expression in Heart Failure Underlies Dysregulation of Action Potential Duration and Myocardial Vulnerability to Injury

The search for new approaches to treatment and prevention of heart failure is a major challenge in medicine. The adenosine triphosphate-sensitive potassium (K(ATP)) channel has been long associated with the ability to preserve myocardial function and viability under stress. High surface expression o...

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Detalles Bibliográficos
Autores principales: Gao, Zhan, Sierra, Ana, Zhu, Zhiyong, Koganti, Siva Rama Krishna, Subbotina, Ekaterina, Maheshwari, Ankit, Anderson, Mark E., Zingman, Leonid V., Hodgson-Zingman, Denice M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786327/
https://www.ncbi.nlm.nih.gov/pubmed/26964104
http://dx.doi.org/10.1371/journal.pone.0151337