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Understanding Genotype-Phenotype Effects in Cancer via Network Approaches
Cancer is now increasingly studied from the perspective of dysregulated pathways, rather than as a disease resulting from mutations of individual genes. A pathway-centric view acknowledges the heterogeneity between genomic profiles from different cancer patients while assuming that the mutated genes...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786343/ https://www.ncbi.nlm.nih.gov/pubmed/26963104 http://dx.doi.org/10.1371/journal.pcbi.1004747 |