Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs

Many organisms lose the capacity to regenerate damaged tissues as they mature. Damaged Drosophila imaginal discs regenerate efficiently early in the third larval instar (L3) but progressively lose this ability. This correlates with reduced damage-responsive expression of multiple genes, including th...

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Detalles Bibliográficos
Autores principales: Harris, Robin E, Setiawan, Linda, Saul, Josh, Hariharan, Iswar K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786413/
https://www.ncbi.nlm.nih.gov/pubmed/26840050
http://dx.doi.org/10.7554/eLife.11588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786413/
https://www.ncbi.nlm.nih.gov/pubmed/26840050
http://dx.doi.org/10.7554/eLife.11588

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