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Registered report: The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

The Reproducibility Project: Cancer Biology seeks to address growing concerns about reproducibility in scientific research by conducting replications of selected experiments from a number of high-profile papers in the field of cancer biology. The papers, which were published between 2010 and 2012, w...

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Detalles Bibliográficos
Autores principales: Fiehn, Oliver, Showalter, Megan Reed, Schaner-Tooley, Christine E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786416/
https://www.ncbi.nlm.nih.gov/pubmed/26943899
http://dx.doi.org/10.7554/eLife.12626