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Translational control of nicotine-evoked synaptic potentiation in mice and neuronal responses in human smokers by eIF2α

Adolescents are particularly vulnerable to nicotine, the principal addictive component driving tobacco smoking. In a companion study, we found that reduced activity of the translation initiation factor eIF2α underlies the hypersensitivity of adolescent mice to the effects of cocaine. Here we report...

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Detalles Bibliográficos
Autores principales: Placzek, Andon N, Molfese, David L, Khatiwada, Sanjeev, Viana Di Prisco, Gonzalo, Huang, Wei, Sidrauski, Carmela, Krnjević, Krešimir, Amos, Christopher L, Ray, Russell, Dani, John A, Walter, Peter, Salas, Ramiro, Costa-Mattioli, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786418/
https://www.ncbi.nlm.nih.gov/pubmed/26928076
http://dx.doi.org/10.7554/eLife.12056