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Translational control by eIF2α phosphorylation regulates vulnerability to the synaptic and behavioral effects of cocaine
Adolescents are especially prone to drug addiction, but the underlying biological basis of their increased vulnerability remains unknown. We reveal that translational control by phosphorylation of the translation initiation factor eIF2α (p-eIF2α) accounts for adolescent hypersensitivity to cocaine....
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786430/ https://www.ncbi.nlm.nih.gov/pubmed/26928234 http://dx.doi.org/10.7554/eLife.12052 |