Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes

GBPs are essential for immunity against intracellular pathogens, especially for Toxoplasma gondii control. Here, the molecular interactions of murine GBPs (mGBP1/2/3/5/6), homo- and hetero-multimerization properties of mGBP2 and its function in parasite killing were investigated by mutational, Multi...

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Detalles Bibliográficos
Autores principales: Kravets, Elisabeth, Degrandi, Daniel, Ma, Qijun, Peulen, Thomas-Otavio, Klümpers, Verena, Felekyan, Suren, Kühnemuth, Ralf, Weidtkamp-Peters, Stefanie, Seidel, Claus AM, Pfeffer, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786432/
https://www.ncbi.nlm.nih.gov/pubmed/26814575
http://dx.doi.org/10.7554/eLife.11479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786432/
https://www.ncbi.nlm.nih.gov/pubmed/26814575
http://dx.doi.org/10.7554/eLife.11479

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