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NAFLD causes selective CD4(+) T lymphocyte loss and promotes hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is the second most common cause of cancer related death. Non-alcoholic fatty liver disease (NAFLD) affects a large proportion of the US population and is considered a metabolic predisposition to liver cancer (1-5). However, the role of adaptive immune responses in NAFL...

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Detalles Bibliográficos
Autores principales: Ma, Chi, Kesarwala, Aparna H., Eggert, Tobias, Medina-Echeverz, José, Kleiner, David E., Jin, Ping, Stroncek, David F., Terabe, Masaki, Kapoor, Veena, ElGindi, Mei, Han, Miaojun, Thornton, Angela M., Zhang, Haibo, Egger, Michèle, Luo, Ji, Felsher, Dean W., McVicar, Daniel W., Weber, Achim, Heikenwalder, Mathias, Greten, Tim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786464/
https://www.ncbi.nlm.nih.gov/pubmed/26934227
http://dx.doi.org/10.1038/nature16969