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Localization of tamoxifen in human breast cancer tumors by MALDI mass spectrometry imaging
BACKGROUND: Tamoxifen is used in endocrine treatment of breast cancer to inhibit estrogen signaling. A set of stratified ER-positive and ER-negative tumor sections was subjected to manual deposition of tamoxifen solution in order to investigate its spatial distribution upon exposure to interaction w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786513/ https://www.ncbi.nlm.nih.gov/pubmed/26965929 http://dx.doi.org/10.1186/s40169-016-0090-9 |