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Localization of tamoxifen in human breast cancer tumors by MALDI mass spectrometry imaging

BACKGROUND: Tamoxifen is used in endocrine treatment of breast cancer to inhibit estrogen signaling. A set of stratified ER-positive and ER-negative tumor sections was subjected to manual deposition of tamoxifen solution in order to investigate its spatial distribution upon exposure to interaction w...

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Detalles Bibliográficos
Autores principales: Végvári, Ákos, Shavkunov, Alexander S., Fehniger, Thomas E., Grabau, Dorthe, Niméus, Emma, Marko-Varga, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786513/
https://www.ncbi.nlm.nih.gov/pubmed/26965929
http://dx.doi.org/10.1186/s40169-016-0090-9