Hypoxia attenuates Hsp90 inhibitor 17-DMAG-induced cyclin B1 accumulation in hepatocellular carcinoma cells

Hypoxia stress plays a pivotal role in tumor formation, proliferation, and invasion. Conventional chemotherapy is less effective in the hypoxia microenvironment of solid tumor. Heat shock protein 90 (Hsp90) is an important molecular chaperone in cancer cells and has been a pharmaceutical target for...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jianming, Li, Huadan, Huang, Zhizhou, He, Yangfan, Zhou, Xueqiong, Huang, Tingyuan, Dai, Peijuan, Duan, Danping, Ma, Xiaojiao, Yin, Qiangbin, Wang, Xiaojie, Liu, Hong, Chen, Size, Zou, Fei, Chen, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786521/
https://www.ncbi.nlm.nih.gov/pubmed/26786409
http://dx.doi.org/10.1007/s12192-015-0664-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786521/
https://www.ncbi.nlm.nih.gov/pubmed/26786409
http://dx.doi.org/10.1007/s12192-015-0664-2

Ejemplares similares