A Model to Study the Impact of Polymorphism Driven Liver-Stage Immune Evasion by Malaria Parasites, to Help Design Effective Cross-Reactive Vaccines

Malaria parasites engage a multitude of strategies to evade the immune system of the host, including the generation of polymorphic T cell epitope sequences, termed altered peptide ligands (APLs). Herein we use an animal model to study how single amino acid changes in the sequence of the circumsporoz...

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Detalles Bibliográficos
Autores principales: Wilson, Kirsty L., Xiang, Sue D., Plebanski, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786561/
https://www.ncbi.nlm.nih.gov/pubmed/27014226
http://dx.doi.org/10.3389/fmicb.2016.00303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786561/
https://www.ncbi.nlm.nih.gov/pubmed/27014226
http://dx.doi.org/10.3389/fmicb.2016.00303

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