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Bacteriocins of lactic acid bacteria: extending the family

Lactic acid bacteria (LAB) constitute a heterogeneous group of microorganisms that produce lactic acid as the major product during the fermentation process. LAB are Gram-positive bacteria with great biotechnological potential in the food industry. They can produce bacteriocins, which are proteinaceo...

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Autores principales: Alvarez-Sieiro, Patricia, Montalbán-López, Manuel, Mu, Dongdong, Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786598/
https://www.ncbi.nlm.nih.gov/pubmed/26860942
http://dx.doi.org/10.1007/s00253-016-7343-9
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author Alvarez-Sieiro, Patricia
Montalbán-López, Manuel
Mu, Dongdong
Kuipers, Oscar P.
author_facet Alvarez-Sieiro, Patricia
Montalbán-López, Manuel
Mu, Dongdong
Kuipers, Oscar P.
author_sort Alvarez-Sieiro, Patricia
collection PubMed
description Lactic acid bacteria (LAB) constitute a heterogeneous group of microorganisms that produce lactic acid as the major product during the fermentation process. LAB are Gram-positive bacteria with great biotechnological potential in the food industry. They can produce bacteriocins, which are proteinaceous antimicrobial molecules with a diverse genetic origin, posttranslationally modified or not, that can help the producer organism to outcompete other bacterial species. In this review, we focus on the various types of bacteriocins that can be found in LAB and the organization and regulation of the gene clusters responsible for their production and biosynthesis, and consider the food applications of the prototype bacteriocins from LAB. Furthermore, we propose a revised classification of bacteriocins that can accommodate the increasing number of classes reported over the last years. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00253-016-7343-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-47865982016-04-09 Bacteriocins of lactic acid bacteria: extending the family Alvarez-Sieiro, Patricia Montalbán-López, Manuel Mu, Dongdong Kuipers, Oscar P. Appl Microbiol Biotechnol Mini-Review Lactic acid bacteria (LAB) constitute a heterogeneous group of microorganisms that produce lactic acid as the major product during the fermentation process. LAB are Gram-positive bacteria with great biotechnological potential in the food industry. They can produce bacteriocins, which are proteinaceous antimicrobial molecules with a diverse genetic origin, posttranslationally modified or not, that can help the producer organism to outcompete other bacterial species. In this review, we focus on the various types of bacteriocins that can be found in LAB and the organization and regulation of the gene clusters responsible for their production and biosynthesis, and consider the food applications of the prototype bacteriocins from LAB. Furthermore, we propose a revised classification of bacteriocins that can accommodate the increasing number of classes reported over the last years. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00253-016-7343-9) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2016-02-10 2016 /pmc/articles/PMC4786598/ /pubmed/26860942 http://dx.doi.org/10.1007/s00253-016-7343-9 Text en © The Author(s) 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Mini-Review
Alvarez-Sieiro, Patricia
Montalbán-López, Manuel
Mu, Dongdong
Kuipers, Oscar P.
Bacteriocins of lactic acid bacteria: extending the family
title Bacteriocins of lactic acid bacteria: extending the family
title_full Bacteriocins of lactic acid bacteria: extending the family
title_fullStr Bacteriocins of lactic acid bacteria: extending the family
title_full_unstemmed Bacteriocins of lactic acid bacteria: extending the family
title_short Bacteriocins of lactic acid bacteria: extending the family
title_sort bacteriocins of lactic acid bacteria: extending the family
topic Mini-Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786598/
https://www.ncbi.nlm.nih.gov/pubmed/26860942
http://dx.doi.org/10.1007/s00253-016-7343-9
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