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Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex

Microglia are the resident immune cells of the brain. Increasingly, they are recognized as important mediators of normal neurophysiology, particularly during early development. Here we demonstrate that microglia are critical for ocular dominance plasticity. During the visual critical period, closure...

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Detalles Bibliográficos
Autores principales: Sipe, G. O., Lowery,, R. L., Tremblay, M-È, Kelly, E. A., Lamantia, C. E., Majewska, A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786684/
https://www.ncbi.nlm.nih.gov/pubmed/26948129
http://dx.doi.org/10.1038/ncomms10905