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Biophysical Characterization and Activity of Lymphostatin, a Multifunctional Virulence Factor of Attaching and Effacing Escherichia coli

Attaching and effacing Escherichia coli cause diarrhea and typically produce lymphostatin (LifA), an inhibitor of mitogen-activated proliferation of lymphocytes and pro-inflammatory cytokine synthesis. A near-identical factor (Efa1) has been reported to mediate adherence of E. coli to epithelial cel...

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Detalles Bibliográficos
Autores principales: Cassady-Cain, Robin L., Blackburn, Elizabeth A., Alsarraf, Husam, Dedic, Emil, Bease, Andrew G., Böttcher, Bettina, Jørgensen, René, Wear, Martin, Stevens, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786716/
https://www.ncbi.nlm.nih.gov/pubmed/26786100
http://dx.doi.org/10.1074/jbc.M115.709600