Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells

During embryonic development, adult haematopoietic stem cells (HSCs) emerge preferentially in the ventral domain of the aorta in the aorta–gonad–mesonephros (AGM) region. Several signalling pathways such as Notch, Wnt, Shh and RA are implicated in this process, yet how these interact to regulate the...

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Detalles Bibliográficos
Autores principales: Souilhol, Céline, Gonneau, Christèle, Lendinez, Javier G., Batsivari, Antoniana, Rybtsov, Stanislav, Wilson, Heather, Morgado-Palacin, Lucia, Hills, David, Taoudi, Samir, Antonchuk, Jennifer, Zhao, Suling, Medvinsky, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786750/
https://www.ncbi.nlm.nih.gov/pubmed/26952187
http://dx.doi.org/10.1038/ncomms10784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786750/
https://www.ncbi.nlm.nih.gov/pubmed/26952187
http://dx.doi.org/10.1038/ncomms10784

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