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Vaginal Fibroblastic Cells from Women with Pelvic Organ Prolapse Produce Matrices with Increased Stiffness and Collagen Content

Pelvic organ prolapse (POP) is characterised by the weakening of the pelvic floor support tissues, and often by subsequent prolapse of the bladder outside the body, i.e. cystocele. The bladder is kept in place by the anterior vaginal wall which consists of a dense extracellular matrix rich in collag...

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Detalles Bibliográficos
Autores principales: Ruiz-Zapata, Alejandra M., Kerkhof, Manon H., Ghazanfari, Samaneh, Zandieh-Doulabi, Behrouz, Stoop, Reinout, Smit, Theo H., Helder, Marco N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786799/
https://www.ncbi.nlm.nih.gov/pubmed/26965792
http://dx.doi.org/10.1038/srep22971