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Antioxidants inhibit advanced glycosylation end-product-induced apoptosis by downregulation of miR-223 in human adipose tissue-derived stem cells

Advanced glycosylation end products (AGEs) are endogenous inflammatory mediators that induce apoptosis of mesenchymal stem cells. A potential mechanism includes increased generation of reactive oxygen species (ROS). MicroRNA-223 (miR-223) is implicated in the regulation of cell growth and apoptosis...

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Detalles Bibliográficos
Autores principales: Wang, Zhe, Li, Hongqiu, Guo, Ran, Wang, Qiushi, Zhang, Dianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786853/
https://www.ncbi.nlm.nih.gov/pubmed/26964642
http://dx.doi.org/10.1038/srep23021