Secreted APE1/Ref-1 inhibits TNF-α-stimulated endothelial inflammation via thiol-disulfide exchange in TNF receptor

Apurinic apyrimidinic endonuclease 1/Redox factor-1 (APE1/Ref-1) is a multifunctional protein with redox activity and is proved to be secreted from stimulated cells. The aim of this study was to evaluate the functions of extracellular APE1/Ref-1 with respect to leading anti-inflammatory signaling in...

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Detalles Bibliográficos
Autores principales: Park, Myoung Soo, Choi, Sunga, Lee, Yu Ran, Joo, Hee Kyoung, Kang, Gun, Kim, Cuk-Seong, Kim, Soo Jin, Lee, Sang Do, Jeon, Byeong Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786854/
https://www.ncbi.nlm.nih.gov/pubmed/26964514
http://dx.doi.org/10.1038/srep23015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786854/
https://www.ncbi.nlm.nih.gov/pubmed/26964514
http://dx.doi.org/10.1038/srep23015

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