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FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus
The endosomal network maintains cellular homeostasis by sorting, recycling and degrading endocytosed cargoes. Retromer organizes the endosomal sorting pathway in conjunction with various sorting nexin (SNX) proteins. The SNX27–retromer complex has recently been identified as a major endosomal hub th...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786876/ https://www.ncbi.nlm.nih.gov/pubmed/26956659 http://dx.doi.org/10.1038/ncomms10939 |