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FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

The endosomal network maintains cellular homeostasis by sorting, recycling and degrading endocytosed cargoes. Retromer organizes the endosomal sorting pathway in conjunction with various sorting nexin (SNX) proteins. The SNX27–retromer complex has recently been identified as a major endosomal hub th...

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Detalles Bibliográficos
Autores principales: Lee, Seongju, Chang, Jaerak, Blackstone, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786876/
https://www.ncbi.nlm.nih.gov/pubmed/26956659
http://dx.doi.org/10.1038/ncomms10939