Bcl-2 is a critical mediator of intestinal transformation

Intestinal tumour formation is generally thought to occur following mutational events in the stem cell pool. However, active NF-κB signalling additionally facilitates malignant transformation of differentiated cells. We hypothesized that genes shared between NF-κB and intestinal stem cell (ISCs) sig...

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Detalles Bibliográficos
Autores principales: van der Heijden, Maartje, Zimberlin, Cheryl D., Nicholson, Anna M., Colak, Selcuk, Kemp, Richard, Meijer, Sybren L., Medema, Jan Paul, Greten, Florian R., Jansen, Marnix, Winton, Douglas J., Vermeulen, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786877/
https://www.ncbi.nlm.nih.gov/pubmed/26956214
http://dx.doi.org/10.1038/ncomms10916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786877/
https://www.ncbi.nlm.nih.gov/pubmed/26956214
http://dx.doi.org/10.1038/ncomms10916

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