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Development and evaluation of solid dispersion of spironolactone using fusion method

INTRODUCTION: Solubility and dissolution of a poor water-soluble drug are the two major barriers for formulation scientists in development of drug delivery. Many of the potent drugs do not show the therapeutic effects due to solubility issues but may show toxicity issues when used in high doses. Sol...

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Detalles Bibliográficos
Autores principales: Shamsuddin, Fazil, Mohammad, Ansari, Shahid Husain, Ali, Javed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787064/
https://www.ncbi.nlm.nih.gov/pubmed/27014621
http://dx.doi.org/10.4103/2230-973X.176490