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Modulation of Hepatic Cytochrome P450 Enzymes by Curcumin and its Pharmacokinetic Consequences in Sprague–dawley Rats

BACKGROUND: Curcumin (CUR) is a polyphenolic component derived from an herbal remedy and dietary spice turmeric (Curcuma longa). OBJECTIVE: The aim of this study was to investigate inhibitory effects of CUR on in vitro cytochrome P450 (CYP) activity and in vivo pharmacokinetic consequences of single...

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Detalles Bibliográficos
Autores principales: Kim, Sang-Bum, Cho, Seung-Sik, Cho, Hyun-Jong, Yoon, In-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787092/
https://www.ncbi.nlm.nih.gov/pubmed/27013798
http://dx.doi.org/10.4103/0973-1296.172965