Cargando…

Modulation of Hepatic Cytochrome P450 Enzymes by Curcumin and its Pharmacokinetic Consequences in Sprague–dawley Rats

BACKGROUND: Curcumin (CUR) is a polyphenolic component derived from an herbal remedy and dietary spice turmeric (Curcuma longa). OBJECTIVE: The aim of this study was to investigate inhibitory effects of CUR on in vitro cytochrome P450 (CYP) activity and in vivo pharmacokinetic consequences of single...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Sang-Bum, Cho, Seung-Sik, Cho, Hyun-Jong, Yoon, In-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787092/ https://www.ncbi.nlm.nih.gov/pubmed/27013798 http://dx.doi.org/10.4103/0973-1296.172965

Ejemplares similares

Pharmacokinetic Interactions of Herbs with Cytochrome P450 and P-Glycoprotein
por: Cho, Hyun-Jong, et al.
Publicado: (2015)

Bioactivity of Curcumin on the Cytochrome P450 Enzymes of the Steroidogenic Pathway
por: Castaño, Patricia Rodríguez, et al.
Publicado: (2019)

Ameliorative Effect of Curcumin on Olanzapine-induced Obesity in Sprague-Dawley Rats
por: Parasuraman, Subramani, et al.
Publicado: (2017)

Curcumin Ameliorates Benzo[a]pyrene-Induced DNA Damages in Stomach Tissues of Sprague-Dawley Rats
por: Kim, Kyeong Seok, et al.
Publicado: (2019)

Pharmacokinetic data of synthetic cathinones in female Sprague-Dawley rats
por: Grecco, Gregory G., et al.
Publicado: (2018)

Reproductive and Developmental Toxicity of Amitraz in Sprague-Dawley Rats
por: Lim, Jeong-Hyeon, et al.
Publicado: (2010)

Evaluation of Memory Enhancing Clinically Available Standardized Extract of Bacopa monniera on P-Glycoprotein and Cytochrome P450 3A in Sprague-Dawley Rats
por: Singh, Rajbir, et al.
Publicado: (2013)

Effect of citral on mouse hepatic cytochrome P450 enzymes
por: Tang, Huaqiao, et al.
Publicado: (2018)

Artificial Intelligence-Assisted Image Analysis of Acetaminophen-Induced Acute Hepatic Injury in Sprague-Dawley Rats
por: Baek, Eun Bok, et al.
Publicado: (2022)

Strain differences in cytochrome P450 mRNA and protein expression, and enzymatic activity among Sprague Dawley, Wistar, Brown Norway and Dark Agouti rats
por: NISHIYAMA, Yoshihiro, et al.
Publicado: (2016)

The Pharmacokinetics of Medetomidine Administered Subcutaneously during Isoflurane Anaesthesia in Sprague-Dawley Rats
por: Kint, Leila T., et al.
Publicado: (2020)

Effects of Intestinal Microbiota on Pharmacokinetics of Crocin and Crocetin in Male Sprague-Dawley Rats
por: Shakya, Rajina, et al.
Publicado: (2020)

Estrogen Deficiency Potentiates Thioacetamide-Induced Hepatic Fibrosis in Sprague-Dawley Rats
por: Lee, Yong Hee, et al.
Publicado: (2019)

Microencapsulated curcumin from Curcuma longa modulates diet-induced hypercholesterolemia in Sprague Dawley rats
por: Ashraf, Humaira, et al.
Publicado: (2022)

Single-dose Intravenous Toxicology Testing of Daebohwalryeok Pharmcopuncture in Sprague-Dawley Rats
por: Sun, Seung-Ho, et al.
Publicado: (2015)

Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats
por: Youn, Nam Hee, et al.
Publicado: (2020)

Effects of Exposure Period on the Developmental Toxicity of 2-Bromopropane in Sprague-Dawley Rats
por: Shin, In-Sik, et al.
Publicado: (2008)

Ovarian neoplasia in the Sprague-Dawley rat.
por: Lewis, D J
Publicado: (1987)

Hematoxicity of Amodiaquine in Sprague-Dawley Rats
por: Saka, W. A., et al.
Publicado: (2012)

Keishibukuryogan is not carcinogenic in Sprague-Dawley rats
por: Kanitani, Masanao, et al.
Publicado: (2016)

Single-dose Intramuscular Injection Toxicology of Danggui Pharmacopuncture (DGP) in Sprague-Dawley Rats
por: Sun, SeungHo, et al.
Publicado: (2015)

The Usage of Curcumin as Chemopreventive Agent for Oral Squamous Cell Carcinoma: An Experimental Study on Sprague-Dawley Rat
por: Maulina, Tantry, et al.
Publicado: (2019)

Toxicity of Single-dose Intramuscular Injection of Samjeong Pharmacopuncture in Sprague-Dawley Rats
por: Kwon, Kang, et al.
Publicado: (2015)

Regulation of the homeostasis of hepatic endoplasmic reticulum and cytochrome P450 enzymes by autophagy
por: Ma, Xiaowen, et al.
Publicado: (2018)

Modulatory effects of Benjakul extract on rat hepatic cytochrome P450 enzymes
por: Samuhasaneeto, Suchittra, et al.
Publicado: (2021)

Expression and Function of Eicosanoid-Producing Cytochrome P450 Enzymes in Solid Tumors
por: Evangelista, Eric A., et al.
Publicado: (2020)

Assessment of the Toxicity and the Stability of Saeng Mak San by Using Repeated Intravenous Injections in Sprague-Dawley Rats
por: Lee, Hwa-Young, et al.
Publicado: (2016)

Physiological and pharmacokinetic effects of multilevel caging on Sprague Dawley rats under ketamine-xylazine anesthesia
por: Dodelet-Devillers, Aurore, et al.
Publicado: (2016)

Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats
por: Forkuo, Arnold Donkor, et al.
Publicado: (2017)

Study on the pharmacokinetics, tissue distribution and excretion of laurolitsine from Litsea glutinosa in Sprague-Dawley rats
por: Tan, Yin-Feng, et al.
Publicado: (2021)

Streptomyces Cytochrome P450 Enzymes and Their Roles in the Biosynthesis of Macrolide Therapeutic Agents
por: Cho, Myung-A, et al.
Publicado: (2019)

Inhibiting Extracellular Cathepsin D Reduces Hepatic Steatosis in Sprague–Dawley Rats †
por: Khurana, Princy, et al.
Publicado: (2019)

Chronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats
por: Ghelani, Hardik, et al.
Publicado: (2019)

28-Day Oral Toxicity of Cadmium Selenide in Sprague-Dawley Rats
por: Kim, Yong Soon, et al.
Publicado: (2009)

Allosteric modulation of cytochrome P450 enzymes by the NADPH cytochrome P450 reductase FMN-containing domain
por: Burris-Hiday, Sarah D., et al.
Publicado: (2023)

A Pilot Study on Single-dose Toxicity Testing of Scolopendrid Pharmacopuncture in Sprague-Dawley Rats
por: Son, Ilhong, et al.
Publicado: (2014)

Succinic acid inhibits the activity of cytochrome P450 (CYP450) enzymes
por: Wang, Hao, et al.
Publicado: (2020)

Effects and Mechanism of Nano-Copper Exposure on Hepatic Cytochrome P450 Enzymes in Rats
por: Tang, Huaqiao, et al.
Publicado: (2018)

Nonalcoholic Fatty Liver Disease (NAFLD) and Hepatic Cytochrome P450 (CYP) Enzymes
por: Jamwal, Rohitash, et al.
Publicado: (2020)

Pharmacokinetics, toxicity, and cytochrome P450 modulatory activity of plumbagin
por: Sumsakul, Wiriyaporn, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_5iub7lbjhkt12j2lmp8ju2p985