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Adiponectin improves NF-κB-mediated inflammation and abates atherosclerosis progression in apolipoprotein E-deficient mice

BACKGROUND: Atherosclerosis is a common pathological basis of cardiovascular disease. Adiponectin (APN) has been shown to have an anti-atherosclerosis effect, and the underlying mechanisms, however, are largely unknown. Nuclear factor κB (NF-κB) has also been regarded as a proatherogenic factor, mai...

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Detalles Bibliográficos
Autores principales: Wang, Xuemei, Chen, Qingjie, Pu, Hongwei, Wei, Qin, Duan, Mingjun, Zhang, Chun, Jiang, Tao, Shou, Xi, Zhang, Jianlong, Yang, Yining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787184/
https://www.ncbi.nlm.nih.gov/pubmed/26965176
http://dx.doi.org/10.1186/s12944-016-0202-y