Hairpins participating in folding of human telomeric sequence quadruplexes studied by standard and T-REMD simulations

DNA G-hairpins are potential key structures participating in folding of human telomeric guanine quadruplexes (GQ). We examined their properties by standard MD simulations starting from the folded state and long T-REMD starting from the unfolded state, accumulating ∼130 μs of atomistic simulations. A...

Descripción completa

Detalles Bibliográficos
Autores principales: Stadlbauer, Petr, Kührová, Petra, Banáš, Pavel, Koča, Jaroslav, Bussi, Giovanni, Trantírek, Lukáš, Otyepka, Michal, Šponer, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787745/
https://www.ncbi.nlm.nih.gov/pubmed/26433223
http://dx.doi.org/10.1093/nar/gkv994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787745/
https://www.ncbi.nlm.nih.gov/pubmed/26433223
http://dx.doi.org/10.1093/nar/gkv994

Ejemplares similares