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Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq

Sequencing DNA fragments associated with proteins following in vivo cross-linking with formaldehyde (known as ChIP-seq) has been used extensively to describe the distribution of proteins across genomes. It is not widely appreciated that this method merely estimates a protein's distribution and...

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Detalles Bibliográficos
Autores principales: Hu, Bin, Petela, Naomi, Kurze, Alexander, Chan, Kok-Lung, Chapard, Christophe, Nasmyth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787748/
https://www.ncbi.nlm.nih.gov/pubmed/26130708
http://dx.doi.org/10.1093/nar/gkv670