Cargando…
Biological chromodynamics: a general method for measuring protein occupancy across the genome by calibrating ChIP-seq
Sequencing DNA fragments associated with proteins following in vivo cross-linking with formaldehyde (known as ChIP-seq) has been used extensively to describe the distribution of proteins across genomes. It is not widely appreciated that this method merely estimates a protein's distribution and...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787748/ https://www.ncbi.nlm.nih.gov/pubmed/26130708 http://dx.doi.org/10.1093/nar/gkv670 |