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Utilizing mapping targets of sequences underrepresented in the reference assembly to reduce false positive alignments
The human reference assembly remains incomplete due to the underrepresentation of repeat-rich sequences that are found within centromeric regions and acrocentric short arms. Although these sequences are marginally represented in the assembly, they are often fully represented in whole-genome short-re...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787761/ https://www.ncbi.nlm.nih.gov/pubmed/26163063 http://dx.doi.org/10.1093/nar/gkv671 |