Mammalian RAD51 paralogs protect nascent DNA at stalled forks and mediate replication restart

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Mammalian RAD51 paralogs are implicated in the repair of collapsed replication forks by homologous recombination. However, their physiological roles in replication fork maintenance prior to fork collapse remain obscure. Here, we report on the role of RAD51 paralogs in short-term replicative stress d...

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Detalles Bibliográficos
Autores principales: Somyajit, Kumar, Saxena, Sneha, Babu, Sharath, Mishra, Anup, Nagaraju, Ganesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787763/
https://www.ncbi.nlm.nih.gov/pubmed/26354865
http://dx.doi.org/10.1093/nar/gkv880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787763/
https://www.ncbi.nlm.nih.gov/pubmed/26354865
http://dx.doi.org/10.1093/nar/gkv880

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