Perturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop

PIP3 is synthesized by the Class I PI3Ks and regulates complex cell responses, such as growth and migration. Signals that drive long-term reshaping of cell phenotypes are difficult to resolve because of complex feedback networks that operate over extended times. PIP(3)-dependent modulation of mRNA a...

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Detalles Bibliográficos
Autores principales: Kiselev, Vladimir Yu., Juvin, Veronique, Malek, Mouhannad, Luscombe, Nicholas, Hawkins, Phillip, Novère, Nicolas Le, Stephens, Len
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787766/
https://www.ncbi.nlm.nih.gov/pubmed/26464442
http://dx.doi.org/10.1093/nar/gkv1015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787766/
https://www.ncbi.nlm.nih.gov/pubmed/26464442
http://dx.doi.org/10.1093/nar/gkv1015

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