Oct-2 forms a complex with Oct-1 on the iNOS promoter and represses transcription by interfering with recruitment of RNA PolII by Oct-1

Oct-1 (POU2f1) and Oct-2 (POU2f2) are members of the POU family of transcription factors. They recognize the same DNA sequence but fulfil distinct functions: Oct-1 is ubiquitous and regulates a variety of genes while Oct-2 is restricted to B-cells and neurones. Here we examine the interplay and regu...

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Detalles Bibliográficos
Autores principales: Bentrari, Fatima, Chantôme, Aurelie, Knights, Andrew, Jeannin, Jean-François, Pance, Alena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787767/
https://www.ncbi.nlm.nih.gov/pubmed/26271992
http://dx.doi.org/10.1093/nar/gkv829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787767/
https://www.ncbi.nlm.nih.gov/pubmed/26271992
http://dx.doi.org/10.1093/nar/gkv829

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