Trans-oligomerization of duplicated aminoacyl-tRNA synthetases maintains genetic code fidelity under stress

Aminoacyl-tRNA synthetases (aaRSs) play a key role in deciphering the genetic message by producing charged tRNAs and are equipped with proofreading mechanisms to ensure correct pairing of tRNAs with their cognate amino acid. Duplicated aaRSs are very frequent in Nature, with 25,913 cases observed in...

Descripción completa

Detalles Bibliográficos
Autores principales: Rubio, Miguel Ángel, Napolitano, Mauro, Ochoa de Alda, Jesús A. G., Santamaría-Gómez, Javier, Patterson, Carl J., Foster, Andrew W., Bru-Martínez, Roque, Robinson, Nigel J., Luque, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787780/
https://www.ncbi.nlm.nih.gov/pubmed/26464444
http://dx.doi.org/10.1093/nar/gkv1020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787780/
https://www.ncbi.nlm.nih.gov/pubmed/26464444
http://dx.doi.org/10.1093/nar/gkv1020

Ejemplares similares