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Hairpins under tension: RNA versus DNA

We use optical tweezers to control the folding and unfolding of individual DNA and RNA hairpins by force. Four hairpin molecules are studied in comparison: two DNA and two RNA ones. We observe that the conformational dynamics is slower for the RNA hairpins than for their DNA counterparts. Our result...

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Detalles Bibliográficos
Autores principales: Bercy, Mathilde, Bockelmann, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787782/
https://www.ncbi.nlm.nih.gov/pubmed/26323319
http://dx.doi.org/10.1093/nar/gkv860