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Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles

Telomerase, a unique ribonucleoprotein complex that contains the telomerase reverse transcriptase (TERT), the telomerase RNA component (TERC) and the TERC-binding protein dyskerin, is required for continued cell proliferation in stem cells and cancer cells. Here we identify SRSF11 as a novel TERC-bi...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hoon, Jeong, Sun Ah, Khadka, Prabhat, Hong, Juyeong, Chung, In Kwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787792/
https://www.ncbi.nlm.nih.gov/pubmed/26286192
http://dx.doi.org/10.1093/nar/gkv844