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Involvement of SRSF11 in cell cycle-specific recruitment of telomerase to telomeres at nuclear speckles
Telomerase, a unique ribonucleoprotein complex that contains the telomerase reverse transcriptase (TERT), the telomerase RNA component (TERC) and the TERC-binding protein dyskerin, is required for continued cell proliferation in stem cells and cancer cells. Here we identify SRSF11 as a novel TERC-bi...
Autores principales: | Lee, Ji Hoon, Jeong, Sun Ah, Khadka, Prabhat, Hong, Juyeong, Chung, In Kwon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787792/ https://www.ncbi.nlm.nih.gov/pubmed/26286192 http://dx.doi.org/10.1093/nar/gkv844 |
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