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In vivo detection and replication studies of α-anomeric lesions of 2′-deoxyribonucleosides

DNA damage, arising from endogenous metabolism or exposure to environmental agents, may perturb the transmission of genetic information by blocking DNA replication and/or inducing mutations, which contribute to the development of cancer and likely other human diseases. Hydroxyl radical attack on the...

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Detalles Bibliográficos
Autores principales: Amato, Nicholas J., Zhai, Qianqian, Navarro, Diana C., Niedernhofer, Laura J., Wang, Yinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787794/
https://www.ncbi.nlm.nih.gov/pubmed/26202973
http://dx.doi.org/10.1093/nar/gkv725