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Elongator-dependent modification of cytoplasmic tRNA(Lys)(UUU) is required for mitochondrial function under stress conditions

To gain a wider view of the pathways that regulate mitochondrial function, we combined the effect of heat stress on respiratory capacity with the discovery potential of a genome-wide screen in Saccharomyces cerevisiae. We identified 105 new genes whose deletion impairs respiratory growth at 37°C by...

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Detalles Bibliográficos
Autores principales: Tigano, Marco, Ruotolo, Roberta, Dallabona, Cristina, Fontanesi, Flavia, Barrientos, Antoni, Donnini, Claudia, Ottonello, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787798/
https://www.ncbi.nlm.nih.gov/pubmed/26240381
http://dx.doi.org/10.1093/nar/gkv765