The interplay between DNA methylation and sequence divergence in recent human evolution

Despite the increasing knowledge about DNA methylation, the understanding of human epigenome evolution is in its infancy. Using whole genome bisulfite sequencing we identified hundreds of differentially methylated regions (DMRs) in humans compared to non-human primates and estimated that ∼25% of the...

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Detalles Bibliográficos
Autores principales: Hernando-Herraez, Irene, Heyn, Holger, Fernandez-Callejo, Marcos, Vidal, Enrique, Fernandez-Bellon, Hugo, Prado-Martinez, Javier, Sharp, Andrew J., Esteller, Manel, Marques-Bonet, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787803/
https://www.ncbi.nlm.nih.gov/pubmed/26170231
http://dx.doi.org/10.1093/nar/gkv693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787803/
https://www.ncbi.nlm.nih.gov/pubmed/26170231
http://dx.doi.org/10.1093/nar/gkv693

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