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Structure and primase-mediated activation of a bacterial dodecameric replicative helicase

Replicative helicases are essential ATPases that unwind DNA to initiate chromosomal replication. While bacterial replicative DnaB helicases are hexameric, Helicobacter pylori DnaB (HpDnaB) was found to form double hexamers, similar to some archaeal and eukaryotic replicative helicases. Here we prese...

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Detalles Bibliográficos
Autores principales: Bazin, Alexandre, Cherrier, Mickaël V., Gutsche, Irina, Timmins, Joanna, Terradot, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787810/
https://www.ncbi.nlm.nih.gov/pubmed/26264665
http://dx.doi.org/10.1093/nar/gkv792