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Global analysis of RNA cleavage by 5′-hydroxyl RNA sequencing
RNA cleavage by some endoribonucleases and self-cleaving ribozymes produces RNA fragments with 5′-hydroxyl (5′-OH) and 2′,3′-cyclic phosphate termini. To identify 5′-OH RNA fragments produced by these cleavage events, we exploited the unique ligation mechanism of Escherichia coli RtcB RNA ligase to...
Autores principales: | Peach, Sally E., York, Kerri, Hesselberth, Jay R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787814/ https://www.ncbi.nlm.nih.gov/pubmed/26001965 http://dx.doi.org/10.1093/nar/gkv536 |
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